|
KMID : 0361120210350010048
|
|
Korean Journal of Transplantation
2021 Volume.35 No. 1 p.48 ~ p.52
|
|
|
Posttransplantation tuberculosis management in terms of immunosuppressant cost: a case report in Myanmar
|
|
Lwin Phyo Wai
Htun Yi Yi
Myint Aung Kyaw
Swe Htar Kyi
|
|
|
Abstract
|
|
|
|
Drug interactions between anti-tuberculosis and immunosuppressive medications after renal transplantation are a common problem in Myanmar. The efficacy of both types of drugs can be reduced during the treatment period, which can lead to graft failure and flare-ups of infection. Drug adjustments, with frequent monitoring and close follow-up, are crucial in this period. Ketoconazole decreases tacrolimus metabolism by inhibiting cytochrome P450-3A5 enzymes and P-glycoprotein. It is cost effective and has been frequently used to reduce the dose and cost of tacrolimus. Here, we report the case of a 56-year-old male renal transplant recipient with anti-tuberculosis medications.
|
|
|
KEYWORD
|
|
|
Post renal transplant tuberculosis, Immunosuppressant cost, Drug Interaction
|
|
|
FullTexts / Linksout information
|
|
|
|
|
|
Listed journal information
|
|
  
|